Author: ZHOU Yan, ZHAO Li-rong , YANG
Abstract: Objective To establish a stable and reliable animal models with dilated cardiomyopathy (dilated cardiomyopathy, DCM) for basic experiments.Methods Male Wistar rats were divided into normal control group and DCM model group,DCM group received intraperitone...
Author: LI Xiao -mei, YANG Yi -ning ,
Abstract: AIM: To explore the changes in extracellular regulated protein kinase (ERK1/2) in the hyper- trophic myocardium induced by pressure overload at the different time courses and to determine the molecular mechanism in the myocardium from hypertrophy to heart...
Author: WUJian-yu WANG Shu-qiu WANG Ba
Abstract: AIM : To study the mechanism of diabetic cardiomyopathy and abnormality of oxygen free radicals. METHODS : The contents of myocardial cytosolic cytochrome C, mitochondria cytochrome C, mitochondrial calcium, NO, MDA and the activity of SOD and NOS were de...
Author: SONG Yan ,ZOU Wen ,LI Xiao-xu
Abstract: Objective To evaluate clinical significances of electrocardiographic changes in patients with hypertrophic cardiomyopathy (HOM). Methods Electrocardiogram was made and analysed in 88 patients with HOM. Results Abnormal electrocardiographic changes of ST-T...
Author: DONG Hongke, SUN Hongping, YAO
Abstract: Objective:To investigate the effects of Qiliqiangxin capsule on heart function and serum factors in a rat model of cardiomyopathy induced by adriamycin.Method:The SD rats were randomly divided into two groups:normal control group and model building group....
Author: LI Jing, LI Xinli, GU Kai ,ZHA
Abstract: Objiective:To explore the relationship between clinical symptoms ,some examinational indexes for cardiac function and serum markers related to renal function in dilated cardiomyopathy patients with heart failure (DCM-HF),and the mechanism.Method:Sixty-one...
Author: XU Maochun, QIU Jianping ,ZHAN
Abstract: Objective:To investigate the long-term effect of cardiac resynchronization therapy (CRT) in patients with dilated cardiomyopathy.Method:Eighteen dilated cardiomyopathy patients with drug-refractory heartfailure received cardiac resynchronous pacing. Check...
Author: HUANG Sisi, WU Weifeng, LIN So
Abstract: Objective:The aim of this study was to observe the level of interleukin-35(IL-35) in peripheral blood mononuclear cells (PBMCs) with dilated cardiomyopathy (DCM),and explore the role of IL-35 in human DCM. Method:Thirty cases of patients with DCM(DCM grou...
Author: KONG Dehua, WANG Ailing ,CHEN
Abstract: Objective:Familial hypertrophic cardiomyopathy (FHCM) is a form of cardiomyopathy with an autosomal dominant inherited disease,which is caused by mutations in at least one of the sarcomeric protein genes. Mutations in the myosin binding protein C genes (M...
Author: WU Hai, LIAO Qinchen ,HE Huiju
Abstract: Objective:To investigate the expression and significance of CD4^+ CD25^+ Foxp3^+ T cells in peripheral blood of patients with dilated cardiomyopathy (DCM). Method:The frequencies of CD4^+ CD25^+ T cells and CD4^+CD25^+Foxp3^+ T cells were detected in 30 p...
Author: LIN Jihong, FAN Ying ,DONG Guo
Abstract: Objective:To investigate the changes of coronary flow reserve (CFR) of patients without heart failure of dilated cardiomyopathy (DCM) by non-invasive transthoracic stress echocardiography before and after the treatment of carvedilol.Method:Forty patients ...
Author: PENG Zhong,ZHOU Re- nxiu , WAN
Abstract: Objective To study the change of heart rate turbulence(HRT) in dilated cardiomy- opathy and its relationship with standard deviation of mormal-to-mormal RR interals (SDNN), left ventrieular ejection fraction(LVEF) and left ventricular end-diastolic diamet...
Author: CUI Feng-zhe,CUI Ying
Abstract: BACKGROUND To observe Shenqifuzheng injection combined with carvedilol and captopril in the treatment of heart failure of ischemic cardiomyopathy.CASE REPORTSThe 70 patients with heart failure and ischemic cardiomyopathy were randomly divided into control...
Author: ZHAO Ying-jie,CHU Jian-min,GUA
Abstract: OBJECTIVE To analyze the relationship between lesion degree and clinical manifestation in patients with arrhythmogenic right ventricular cardiomyopathy(ARVC).METHODSThe 61 cases of data with ARVC were retrospectively analyzed,and patients with ARVC divide...
Author: CHEN Wei, CHEN Wen-jie, XIA Ya
Abstract: Objective This article was designed to observe the effects of astragalus polysaccharides (APS) on glucose and lipid metabolism, and on expressions of proxisome proliferator activated receptors-α (PPAR-α) and its downstream genes in diabetic hamsters cardi...